Before studies Darko Karajic learned guitar with Dusan Saponja, Nadezda Kondic, Dusan Bogdanovic and Vera Ogrizovic.
He graduated from the Music Academy in Zagreb in the class of István Römer, got MA at the Faculty of Music in Belgrade, and is currently completing the PhD studies.
As a member of ensembles Musica Antiqua, Ars Nova and Renesans he has performed in all major venues and festivals in former Yugoslavia, as well as in most European countries. Karajic is a Docent at the Faculty of Music in Belgrade. From 1994 he teaches lute at the Department for Early Music in Music School Slavenski. From 2007 he is a lecturer at the Academy of Fine Arts in Belgrade and from 2011 he teaches at the Music Academy in Eastern Sarajevo.
Darko Karajic is a member of the Association of Musical Artists of Serbia and the Yugoslav Association of classical guitarists.